Abstract. Our glaciological studies were conducted for the periods of 1956-1989, 1989-2001 and 2001-2012 and are based on Landsat TM/ETM+ data analysis. A well- established semi-automated band ratio technique was applied for glacier mapping. The result showed a comparatively higher shrinkage rate (-1.02%) than rates in other glacierized areas of Central Asian mountains, including Altai, Tien Shan and Pamir. We also analyzed long-term climatic and runoff fluctuations for the different sub-basins of the Karatal River. A positive trend in annual discharge was detected in almost all the glacierized tributaries of the Karatal River during the last half of the century.